Digestly

Mar 21, 2025

Agentic Products & Crypto Clarity: Startup Insights 🚀

Startup
This Week in Startups: Discussion on the implications of unclear crypto regulations and the role of XRP.
a16z: The discussion focuses on the development and application of agentic products, particularly in the context of digital workers for revenue teams, emphasizing customer outcomes and adaptability to rapidly changing AI technologies.
a16z: The discussion focuses on leveraging technology and community-based care to improve Medicaid healthcare delivery, emphasizing the importance of predictive models and social care integration.

This Week in Startups - Why Did The SEC Cave to XRP?

The conversation critiques Brad Garlinghouse's stance on crypto regulations, suggesting that Ripple's actions skirted securities laws. Despite unclear regulations, allowing the sale of centralized tokens without consequences could destabilize markets. The crypto community advocates for less regulation to foster innovation, but the expected boom in transformative projects hasn't materialized. XRP's practical use is questioned, with crypto likened to a Ponzi scheme due to the speculative nature of many coins.

Key Points:

  • Brad Garlinghouse criticized for allegedly skirting securities laws.
  • Unclear regulations could lead to market chaos if unchecked.
  • Crypto community desires less regulation to become a global hub.
  • Despite potential, transformative crypto projects are lacking.
  • XRP's practical use is questioned; crypto likened to a Ponzi scheme.

Details:

1. 🚀 Brad Garlinghouse's Bold Stance on Crypto Law

  • Brad Garlinghouse highlights the misuse of legal tactics in the crypto industry, referring to it as 'lawfare,' which he argues is a strategic use of legal proceedings to stifle competition and innovation.
  • He calls for significant regulatory reform to address these issues, pointing out that such legal practices hinder the industry's growth and development.
  • Garlinghouse provides examples of how 'lawfare' has been used to unfairly target crypto companies, suggesting that these actions are often more about competitive advantage than genuine legal concerns.
  • He argues that the current legal framework is outdated and not suited to the fast-paced nature of the crypto industry, which requires a more supportive regulatory environment.
  • Garlinghouse's stance is a call to action for industry leaders and policymakers to collaborate on creating a legal framework that encourages innovation rather than suppresses it.

2. ⚖️ Skirting Securities Law and Market Chaos

  • Bypassing securities law reveals significant regulatory gaps, suggesting the need for immediate legislative attention to close these loopholes.
  • The sale of $1 billion in centralized tokens, without legal intervention, highlights a critical oversight in financial oversight, posing risks of unchecked market behavior.
  • This oversight could lead to significant market chaos, emphasizing the necessity for stronger regulatory frameworks to ensure market stability and protect investors.
  • Specific examples include the potential for fraudulent activities and unchecked speculative bubbles if current regulations are not strengthened.

3. 🌐 The Debate on Crypto Regulation and Innovation

  • Advocates for minimal crypto regulation argue it could make a country the global crypto hub, boosting innovation.
  • Current regulations are believed to stifle innovation in the crypto sector.
  • A regulatory 'blank slate' might lead to a surge in innovative crypto projects, akin to a 'Cambridge explosion.'
  • However, minimal regulation poses risks such as increased fraud and instability in the crypto markets.
  • Examples of varying regulatory approaches include countries like Switzerland, which has attracted many crypto businesses through favorable regulations, and China, which has strict controls limiting innovation.

4. 🔍 Examining the Reality of Crypto Projects and Ponzi Fears

4.1. Concerns About Ponzi Scheme Characteristics

4.2. Questioning Practical Utility

4.3. Speculative Nature of Cryptocurrencies

a16z - The Future of Digital Workers

The conversation highlights the importance of agentic products, which are designed to plan, reason, and improve over time, in delivering customer outcomes. The speaker discusses the challenges and complexities of building such products, especially in B2B applications where subjective factors like content quality and lead qualification are involved. The company, 11x, has developed two main products: Alice, an AI SDR for automating sales outreach, and Mike, a voice agent for handling inbound and outbound communications. These products aim to simplify complex processes for revenue teams by leveraging both first-party and third-party data, and integrating seamlessly with existing workflows. The speaker also addresses the rapid evolution of AI technologies and the need for companies to adapt quickly. They discuss the decision to rearchitect their products to incorporate new advancements, balancing the need for innovation with maintaining existing customer satisfaction. The company emphasizes testing and integrating new models to ensure the best outcomes for customers, highlighting the importance of being open to change and focusing on customer success. The discussion also touches on the challenges of scaling while maintaining product quality and the strategic decisions involved in managing multiple products and customer demands.

Key Points:

  • Agentic products must plan, reason, and improve over time to deliver effective customer outcomes.
  • 11x's products, Alice and Mike, automate sales and communication tasks, integrating with existing systems to simplify processes for revenue teams.
  • Rapid AI advancements require companies to adapt quickly, balancing innovation with customer satisfaction.
  • Testing and integrating new models is crucial for optimizing product performance and achieving customer success.
  • Scaling while maintaining product quality involves strategic management of resources and customer demands.

Details:

1. 🤖 Customer-Centric Digital Workers: The Heart of 11x

  • The company emphasizes customer outcomes by leveraging digital workers, which prioritize efficiency and effectiveness in delivering desired results.
  • Digital workers are used to transform traditional agent-based processes, ensuring that customer needs and results are prioritized.
  • A strategic shift has been made from traditional methods to digital solutions, exemplifying a commitment to improving customer satisfaction and engagement.
  • Specific case studies demonstrate a significant reduction in processing time and an increase in customer satisfaction due to the implementation of digital workers.

2. 🧠 Agentic Products: Defining and Understanding Their Role

2.1. Understanding 'Agentic' in Marketing

2.2. Role of Large Language Models in Agent Companies

3. 🛠️ Tackling Complex B2B Applications: Challenges and Solutions

  • Agentic products struggle with non-deterministic outputs, requiring users to adjust expectations about consistent results. This poses a challenge in managing user expectations and ensuring satisfaction.
  • User interfaces and experiences play a crucial role in integrating agentic systems, as traditional web and mobile interfaces have set specific expectations over the past 25 years. These systems must adapt to these established norms to ensure user acceptance.
  • Code generation within agentic systems is considered mature, showcasing capabilities in planning, execution, and error-based iteration, highlighting the potential for efficiency improvements in software development processes.
  • Verticalized B2B agentic applications introduce complexities beyond basic functionalities, necessitating more sophisticated solutions to address industry-specific needs and enhance operational effectiveness.

4. 💼 Meet Alice and Mike: Digital Workers Revolutionizing Revenue Teams

  • 11x is developing digital workers aimed at revenue teams, claiming these workers deliver human-like results.
  • Alice, an AI-powered Sales Development Representative (SDR), can engage prospects across multiple channels and drive qualified meetings and pipeline growth.
  • Alice utilizes first-party CRM data and an extensive warehouse of third-party data to target website visitors effectively.
  • The goal is to simplify campaign automation for go-to-market teams, making complex processes run on autopilot.
  • Alice abstracts the complexities of finding leads, conducting deep research, and scaling personalized outreach across various channels for improved conversion.
  • Mike, another digital worker, complements Alice by optimizing back-end processes to ensure seamless integration and data flow across platforms.
  • Mike enhances efficiency by automating data entry and synchronization tasks, allowing human team members to focus on strategic activities.
  • Together, Alice and Mike aim to revolutionize the efficiency and effectiveness of revenue teams by handling both front-end engagement and back-end operations.

5. 🎯 Blending Agentic and Orchestrated Tasks for Optimal Outcomes

  • Mike, the second product, is a voice agent designed for inbound and outbound use cases, capable of operating across multiple languages and integrating with customer workflows, such as CRM and calendaring software, to enhance team performance.
  • The company prioritizes customer outcomes by determining whether the use of agents is necessary. The success of digital workers is measured by customer results.
  • Tasks are categorized as agentic or non-agentic, and the focus is on selecting the best technology for optimal outcomes. The company adopts a purist approach in evaluating technology effectiveness for specific tasks.
  • By integrating agentic tasks (self-driven) and orchestrated tasks (managed or automated), the company ensures that each task is handled by the most suitable technology, thereby enhancing overall efficiency and effectiveness.
  • This strategic blending allows for a seamless customer experience, as the system can dynamically adjust to different needs, ensuring that both agentic and orchestrated tasks contribute to optimal outcomes.
  • Examples of successful implementations include improved response times and increased customer satisfaction, as the system is able to leverage the strengths of both task types to meet customer needs effectively.

6. 🚀 Adapting to Change: Product Evolution and Industry Shifts

  • The market has changed rapidly over the last 12 months, requiring quick adaptation of product strategies to remain competitive.
  • Agent frameworks and multimodal models have significantly shifted the industry landscape, offering new opportunities for innovation.
  • A new model introduced was projected to increase ROI by 20%, leading to rapid testing and implementation to capitalize on this potential.
  • A voice-based solution has evolved significantly over the last six months, overcoming challenges like background noise and improving natural speech synthesis.
  • Advancements in voice-to-voice models and integrated speech-to-text and inference models have enhanced naturalness and reduced latency.
  • The company balances rapid deployment of new models with a focus on maintaining customer-centric outcomes, ensuring that innovations align with user needs.

7. 🔄 Rebuilding for the Future: Innovation and Transition

  • Voice agents need to be intelligent, natural-sounding, and accurate; most companies only achieve one or two of these, whereas achieving all three is essential.
  • The decision to completely re-architect the product (Alice and Mike) was driven by advancements that promised increased customer value.
  • A strategic analysis comparing existing platform projections versus a complete rebuild over a few months revealed the latter would deliver superior results.
  • The transition management involved dedicating the majority of the team to the new product while a small team maintained the old product with minimal feature development.
  • Challenges during the transition included balancing resources and maintaining client satisfaction, yet it led to a faster-than-expected product rollout.
  • The new product was released faster than anticipated, demonstrating impressive team performance and strategic alignment.

8. 🧬 Continuous Testing: Integrating New Models for Success

8.1. Integration Strategies

8.2. Testing Methodologies

9. 📊 Data-Driven Customer Success: Insights and Strategies

9.1. 📊 Data-Driven Strategies to Enhance Customer Success

9.2. 🔍 Evaluating and Implementing Data-Driven Strategies

10. 📈 Innovating the Sales Infrastructure: Staying Ahead

10.1. 📈 Innovating the Sales Infrastructure: Staying Ahead

10.2. 🔗 Collaboration with Emerging Companies and Technologies

11. 🌐 Balancing Growth and Exploration: Navigating Scale Challenges

  • To effectively manage scale and feature development, companies should allocate resources to both areas on a weekly basis, shifting focus as required by current demands.
  • Implementing weekly strategic themes allows organizations to flexibly prioritize between scaling and accelerating features, ensuring balanced growth.
  • Customer feedback is vital, but maintaining alignment with core mission objectives prevents product drift despite evolving demands.
  • Digital workers must achieve results comparable to human capabilities without transitioning into traditional SaaS solutions, preserving the unique value proposition.
  • Declining custom integration requests while emphasizing core platform strengths can bolster product value and enhance customer retention.
  • A deep understanding of customer challenges is crucial; however, solutions should not simply replicate customer suggestions to avoid overly complex products.
  • Launching multiple products early may defy conventional wisdom, but it can effectively meet diverse customer needs and support broader strategic goals.

12. 🌟 Multi-Product Strategy: Early Diversification and Design Lessons

12.1. Multi-Product Strategy: Early Diversification

12.2. Design Lessons: Early Involvement

13. 🔍 Enhancing User Experience: Market Positioning and Trust

  • Incorporating transparency by showing users each step the AI agent takes, such as crawling websites and writing research reports, helps build customer trust.
  • Relocating to San Francisco, the 'mecca of AI agents,' is seen as a strategic move to accelerate development by leveraging collective intelligence and peer learning.
  • Adopting a more opinionated approach in guiding customers on using the product effectively could have improved customer satisfaction and set clear success metrics.
  • To address rapidly changing market conditions and AI tooling, hiring practices emphasize speed, ownership, and the ability to handle chaos.
  • Success is defined by customer success, with a focus on deep ownership and the willingness to adapt to new models and features.

14. 👥 Building an Agile Team: Hiring for Innovation and Growth

  • Hire individuals who are adaptable and capable of pivoting to focus on outcomes that drive better results, enhancing team agility.
  • Prioritize leaders who combine vision and strategy with the ability to engage deeply in execution, ensuring they can scale their involvement based on project needs.
  • Target former founders for leadership roles, leveraging their experience in strategic pivots and hands-on execution to drive innovation and growth.
  • Focus on building a team where both leaders and members are not 'married' to their work but are driven by achieving strategic goals.

a16z - Scaling Medicaid Innovation with Rajaie Batniji, Sanjay Basu, and Afia Asamoah

The conversation highlights the journey of healthcare professionals transitioning from traditional roles to innovative health tech solutions aimed at improving Medicaid services. The focus is on using technology, such as machine learning models, to predict and prevent unnecessary acute care, thereby reducing costs and improving patient outcomes. The approach involves community health workers and a public benefit corporation model to ensure social responsibility and financial sustainability. The discussion also covers the challenges and strategies for scaling these solutions, emphasizing the need for partnerships and systemic changes in healthcare delivery.

Key Points:

  • Leverage technology to predict and prevent unnecessary acute care, reducing costs and improving outcomes.
  • Use community health workers to provide care outside traditional clinical settings, focusing on social needs.
  • Incorporate as a public benefit corporation to balance financial sustainability with social responsibility.
  • Develop partnerships with healthcare providers and community organizations to scale solutions.
  • Focus on rising risk patients to intervene early and prevent high-cost healthcare episodes.

Details:

1. 🎶 Setting the Stage with Music 🎶

  • The segment does not contain actionable insights or specific metrics as it primarily consists of music without verbal content.

2. 👩‍⚖️ AIA's Career Path: From Google to Waymark 👩‍⚖️

  • AIA was recruited in 2014 as the first lawyer to support Health tech product development at Google, highlighting the importance of legal expertise in tech innovation.
  • The decision to join Google was influenced by AIA's career-long focus on leveraging technology to enhance access and clinical outcomes, particularly for underserved populations. This reflects an early recognition of digital health's potential.
  • AIA's background in medical device and biotech sectors provided the relevant experience for this role, emphasizing the crossover between traditional biotech and emerging digital health sectors.
  • The opportunity at Google arose before digital health became mainstream, illustrating foresight in recognizing the potential of technology in extending clinical care beyond traditional settings.
  • At Waymark, AIA continues to leverage their expertise to drive innovation in digital health, focusing on improving access and outcomes for underserved communities. This role further underscores the strategic importance of digital health solutions in modern clinical practices.

3. 🏥 Sanjay's Primary Care Practice and Medicaid Focus 🏥

  • Sanjay spent nine years at Google focusing on how technology can impact healthcare delivery, where he developed a deep understanding of integrating tech solutions in medical workflows.
  • In 2021, leveraging his experience, Sanjay began testing new ideas aimed at transforming community care delivery, particularly for Medicaid patients, ensuring technology supports and enhances the work of healthcare providers.
  • He emphasizes the critical role of technology in enabling care delivery through collaboration with physicians and nurses to understand real-world workflows and challenges.
  • Sanjay's connection with the a16z talent team facilitated introductions to investors interested in innovative healthcare solutions, aiding in the development and scaling of his ideas.
  • His approach focuses on using technology to streamline processes, enhance patient outcomes, and reduce costs in Medicaid practices.

4. 🩺 Addressing Healthcare Challenges: From Collective Health to Waymark 🩺

  • Healthcare companies are increasingly resembling consumer companies in their approach, emphasizing customer-centric services.
  • Sanjay, leading clinical efforts at Waymark, continues to practice medicine, providing insights from direct patient interaction, especially with Medicaid members.
  • His work in primary care, particularly with Medicaid and Medicare patients, highlights the socio-economic factors influencing healthcare interventions.
  • Waymark's holistic approach aims to deliver clinically effective and practically deliverable solutions to patients.
  • The team backing Waymark has significant experience, with leaders like R being repeat founders, providing seasoned expertise in scaling startup organizations.
  • R's background includes a PhD focused on healthcare payment systems in low-income settings, bringing a deep understanding of financial structures in healthcare.
  • Waymark's strategic initiatives include tailored interventions for Medicaid members, addressing specific socio-economic challenges they face.
  • Examples of interventions include personalized care plans and community-based support systems to improve access and outcomes for low-income patients.

5. 🔍 The Growing Demand and Financial Pressure in Medicaid 🔍

  • Medicaid is the largest and most readily addressable challenge in US healthcare, with significant creativity and capital focused on Medicare and employer segments rather than Medicaid.
  • Approximately 20% of Americans are on Medicaid, with projections suggesting this could increase to 25%, indicating a substantial portion of the population relies on Medicaid plans for healthcare access.
  • The speaker underscores the transformative potential of leveraging technology and talent to address Medicaid challenges, suggesting that significant improvements could be achieved within a relatively short timeframe.
  • There is a pressing need for innovation in the Medicaid sector, which has historically received less attention compared to Medicare and employer-based healthcare solutions.
  • Strategies for transformation include adopting AI-driven analytics to improve patient outcomes and operational efficiency, as well as enhancing personalized care through telehealth solutions.
  • Investing in workforce development and training is crucial to equip healthcare professionals with the necessary skills to effectively utilize new technologies within Medicaid services.

6. 🚀 Innovating Medicaid Care Delivery: Waymark's Mission and Model 🚀

6.1. Challenges in Medicaid Care Delivery

6.2. Waymark's Strategic Solutions and Impact

7. 🏢 The Role of Public Benefit Corporations in Healthcare 🏢

  • Public Benefit Corporations (PBCs) focus on not only financial sustainability but also a social charter aimed at increasing access and quality of healthcare for Medicaid patients.
  • Investment in PBCs is compelling due to an existing evidence base and their ability to scale and implement proven models.
  • PBCs are structured to ensure that even if leadership changes, the commitment to social goals remains integral to the business model.
  • The healthcare model developed by PBCs like weark is designed to service underserved populations indefinitely, ensuring long-term impact.
  • As a PBC, there is an expectation of aligning with social missions while maintaining financial viability, setting clear expectations for stakeholders and directors.

8. 📊 Waymark's Clinical Outcomes and Rising Risk Signal 📊

  • Waymark's Rising Risk Signal Prediction Framework achieved a nearly 25% reduction in emergency room visits and hospitalizations for ambulatory care conditions.
  • The study involved over 60,000 patients across Health Plans in Washington and Virginia, showcasing real-world impact on Medicaid members.
  • Machine learning models used in Waymark's framework predicted ER or hospital visits with more than 90% accuracy.
  • The focus was on preventing conditions like urinary tract infections and asthma exacerbations through better primary care.

9. 🔬 Leveraging Machine Learning for Better Healthcare Delivery 🔬

  • Early intervention using machine learning to distribute inhalers reduced emergency room visits for asthma patients during wildfire smoke events.
  • Support teams including community health workers, behavioral health therapists, and pharmacists surround primary care providers to meet Medicaid patient needs.
  • Machine learning models identified which of the 60,000 patients needed early attention, improving focus and efficiency.
  • Emergency room visits were reduced by 25% compared to a control group.
  • Healthcare access and quality outcomes improved by 11 percentiles, significantly higher than the typical 2-3 percentile increase.
  • Two-thirds of patient-set goals were achieved, emphasizing a patient-centered approach.
  • The algorithm, published in Nature Scientific Reports, predicts acute care usage, driving cost reductions.
  • Unnecessary acute care use was reduced by 23%, and ambulatory care-sensitive hospitalizations decreased by 48%.
  • Pharmacy and primary care spending increased due to better medication adherence and first-time primary care access.
  • The approach is seen as a 'win-win-win,' reducing unnecessary acute care, saving costs, and improving patient outcomes.

10. 🧠 Precision Targeting and Data Science in Healthtech 🧠

10.1. Reducing Healthcare Costs and Improving Quality

10.2. Identifying Rising Risk Patients

10.3. Community-Based Care Model

10.4. Participatory Data Science and Efficiency

10.5. Enhanced Predictive Modeling and Automation

11. 🎯 Scaling Innovations in Medicaid and Value-Based Care 🎯

11.1. Precision Targeting in Healthcare Interventions

11.2. Challenges and Strategies for Scaling

11.3. Adapting to Medicaid and Care Delivery Constraints

11.4. Innovations and Impact

12. 🤝 Building Community Trust and Collaboration in Healthcare 🤝

  • Healthcare operates effectively at the 'Speed Of Trust', emphasizing the importance of strong local relationships and personal interactions.
  • Community health workers attending appointments in person significantly enhance patient communication and care dynamics.
  • Interfacing with community organizations across the country is crucial for startups aiming to support families and communities holistically.
  • Innovative models for Medicaid Healthcare have been launched and scaled, showcasing new approaches to community health management.